Admet Study of Phytochemicals Used In Autoimmune Disease

Pusegaonkar, Rucha; Jain, Rushabh; Kulkarni, Mandar; Magar, Omkar; Deshmukh, Meera; Tilak, Pranati

dc.contributor.author	Pusegaonkar, Rucha
dc.contributor.author	Jain, Rushabh
dc.contributor.author	Kulkarni, Mandar
dc.contributor.author	Magar, Omkar
dc.contributor.author	Deshmukh, Meera
dc.contributor.author	Tilak, Pranati
dc.date.accessioned	2024-04-29T05:22:39Z
dc.date.available	2024-04-29T05:22:39Z
dc.date.issued	2023-07
dc.identifier.citation	Admet Study of Phytochemicals Used In Autoimmune Disease	en_US
dc.identifier.issn	2581-9879
dc.identifier.issn	0076-2571
dc.identifier.uri	http://localhost:8080/xmlui/handle/123456789/16027
dc.description.abstract	Autoimmune disease is a complex term, which describes immune system attacks as a breakdown of tolerance to auto reactive immune cells. It is associated with genetic, infectious,environmental predisposing factor.The use of herbal medicines in autoimmune significantly act on immune system and improves them. Tetrandrine (Tet), a bis-benzylisoquinoline alkaloid isolated from the creeper Stephania tetrandra S Moore, belong to family Menispermacae has been used for decades in Mainland China to treat patients autoimmune illnesses rheumatism. Punarnavine, alkaloid obtained from Boerhavia diffusa belong to familyNyctaginaceae. Punarnavine significantly reduced the LPS induced elevated levels of proinflammatory cytokines such as TNF-α, IL-1β, and IL-6 in mice. This review summarizes ADMET Study of tetrandrine and punarnavine by software analysis SWISS ADME and ADME2.0 and determine drug likeliness.(1)	en_US
dc.language.iso	en	en_US
dc.publisher	Kesari Mahratta Trust	en_US
dc.relation.ispartofseries	Vol - I;Issue - I
dc.subject	Tetrandrine	en_US
dc.subject	Punarnavine	en_US
dc.subject	Immunomodulator	en_US
dc.subject	Lipophilicity	en_US
dc.subject	Lipinski Rule	en_US
dc.subject	AMES toxicity	en_US
dc.title	Admet Study of Phytochemicals Used In Autoimmune Disease	en_US
dc.type	Article	en_US